Eurasia Research Quarterly Newsletter HBSRA (October 2019 - December 2019)
Updated: Mar 5, 2020
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Eurasia Research International Conference began with opening remarks by Honourable Keynote speaker highlighting the main context on Health Issues. The main aim of this conference was:
The main aim of this conference was:
Advancement of academic knowledge through encouraging research activities.
To create a global community of scholars
Promotion of innovative thinking and ideas on a global platform
Making knowledge accessible to one and all using technology and ideas
Contributing to making the world a better place to live
Our worthy Keynote speakers open up the conference enlightening participants with their speech. Here is our list of keynote speakers who participated in our conference.
Eurasia Research makes continuous efforts in transforming the lives of people around the world through education, application of research & innovative ideas. In order to Promote Young Researchers, Eurasia Research International conferences, Provides Young Research Scholarship in the form of a full Registration fee waiver to participate in such events. This gives immense encouragement to the researchers who have brilliant ideas to exhibit their research work on the International platform. Eurasia Research aims for promoting research and talent of scholars by giving the scholarship to 5 selected applicants for each conference.
Name of Person Attending: Navdeep Kaur Affiliation: Postgraduate Student, Department of Social Work, University of Delhi, New Delhi, India
Paper Title: Impact of Menopause on Quality of Life Among Indian Women
Abstract: Research Objectives: The objective of the study was to assess the impact of menopause on the quality of life of Indian women.ethodology:155 women, in the age range of 40 to 60 years, from various parts of India, were included in the study. Menopause-specific Quality of Life (MENQOL) questionnaire was used to assess the presence of symptoms in vasomotor, psychosocial, physical and sexual domains. Menopausal status was categorized as Late perimenopausal, Early perimenopausal, Premenopausal and postmenopausal.
Findings: The average age of participants was 50.7 years with an average BMI of 25.9. The largest no. of women were in the postmenopausal status (n=115), followed by premenopausal (n=19), early perimenopausal (15) and late perimenopausal (n=6) status. Most common symptom in vasomotor domain was sweating (38.06%), in psychosocial domain feeling anxious (25.80%) and depressed (25.16), in physical domain decrease in physical strength (49.67%), feeling tired (48.38%), lack of energy (47.74%), low backache (47.74%), aching in muscles and joints (46.45%) whereas in sexual domain mild vaginal dryness during intercourse (30%) and change in sexual desire (28.67%).
Research outcomes: The menopausal symptoms lasted many years after the cessation of menstruation. 25-50% of the prevalence rate in various domains indicates a need to adopt a multidimensional approach, for the better management of menopausal symptoms.
Future Scope: Future study may be carried out with an equal sample size in all the categories of menopausal status to identify the relationship between the severity of menopausal symptoms and menopause status.
Keywords: Menopause, Quality of Life, MENQOL questionnaire.
In each, Eurasia International Conference, Best Paper Award is given to Best Researches. In the Healthcare & Biological Sciences Research Association (HBSRA), the Best paper award is given to the participants with the best scholarly paper submitted and presented at the conference.
Name of Person Attending: Dr. Pradeep Kumar
Affiliation: Life Science Department, Higher Education Commission, Haryana, India
Paper Title: Ultrastructural changes in testes of albino rats exposed to electromagnetic radiation
Abstract: The possible adverse reproductive effects resulting from exposure to Electromagnetic fields (EMF) are currently of great public concern. The objective of the present study is to reveal possible effects of Electromagnetic fields emitted from a CDMA mobile phone on DNA damage in rat sperms. After the clearance from the Institutional Animal Ethical Committee (IAEC) M.D.U. Rohtak, approximately 6 weeks old Swiss albino rats were procured from LLRUVAS, Hisar, Haryana. Rats were housed in plastic cases with 3 per cage in a room maintained at 24 ± 1o C and 50 ± 5 % humidity with an alternating 12 h light-dark cycle. All animals were maintained at an animal care facility according to the guidelines for the use and care of laboratory animals and food and water were available ad libitum. After one week of acclimatization, rats were grouped into 2 experimental groups exposed under electromagnetic radiation emitted from a CDMA mobile phone. The experimental group was exposed to 3hrs exposure followed by 30 minutes rest then again 3 hrs exposure and the control group was kept away from the radiation exposure. Scanning and Transmission Electron microscopic micrographs from both of the groups revealed that the extent of ultrastructural damage was higher in the experimental group as compared to the control group. Further research on the molecular basis of current findings will help us to correlate the radiation exposure from mobile phones and male infertility in a better way.
Keywords: Radio Frequency Electromagnetic Fields (RF-EMF), mobile phone, Swiss albino rats, ultrastructural damage.
Name of Person Attending: Ma. Reina Rose Gulmatico
Affiliation: College of Allied Health, Nursing Department, National University Manila, Manila, Philippines
Paper Title: The Effect of Swaddle Bath in the Thermoregulation and Quality of Sleep among Infants
Abstract: Background: Thermoregulation is the ability to balance heat production and heat loss in order to maintain body temperature with a certain normal range. Infants are not as adaptable as adults to temperature change. On the other hand, sleep is another physiologic need among infants. Some infants sleep only for two to three hours at a time. Rocking an infant to sleep is being done to provide warmth and security for the infant. One of the responsibilities a mother should give to her child is bathing. However, bathing is one of the most nerve-wracking experiences that an infant would face. This study determined the effect of swaddle bath in the thermoregulation and quality of sleep among infants in the community.
Methodology: This quantitative, quasi-experimental, pre-posttest research design compared the relative outcomes of Swaddle and Conventional Bath on the thermoregulation and quality of sleep among 36 infants using a self-made research tool adapted from the Brief Infant Sleep Questionnaire (BISQ). The purposive sampling design was used; wherein eighteen (18) of them were assigned in the experimental group and another eighteen (18) in the control group. Weighted mean was used to measure the average difference in the temperature and quality of sleep of the experimental group before and after receiving the Swaddle Bath. The paired sample t-test evaluated the significant difference between the temperature and quality of sleep of the experimental and control group before and after the bath.
Results: The results showed that there is a significant difference in the thermoregulation of the infants before and after the bath in the swaddle bath group and not found in the conventional group. In terms of the mean duration of sleep, infants in the conventional group are greater than in the swaddle group. In terms of duration of wakefulness, the decrease in the mean duration in the conventional group is higher than the swaddle group. There is a significant difference between the swaddle and conventional group in terms of the average number of wakefulness and duration to put the infant to initiate sleep.
Conclusion: Overall, a swaddle bath is effective in maintaining thermoregulation and improving the quality of sleep among infants.
Keywords: swaddle bath; conventional bath; infant; thermoregulation; sleep pattern
Name of Person Attending: Dian Hudiyawati
Affiliation: School of Nursing, Faculty of Health Sciences, Universitas Muhammadiyah Surakarta, Solo, Central Java, Indonesia
Paper Title: Correlation between Social Support and Self-Care Behaviour among Patients with Congestive Heart Failure
Abstract: Heart failure is a condition that heart unable to pump blood to meet the needs of oxygen and nutrients to body tissues. Heart failure is one type of chronic disease that needs treatment for long-term care. Self-care management is an important aspect to improve the quality of life of the patients. Social support affects the psychological response and self-management of these patients. The purpose of this study was to identify the relationship between social support and self-care behavior in patients with congestive heart failure (CHF). This type of research is a cross-sectional design. Data analysis used Chi-Square test. The recent study involved 67 respondents that used the accidental sampling technique. Medical Outcomes Study-Social Support Survey (MOS-SSS) and Self-Care Heart Failure Index (SCHFI) was used to collect the data. The results showed that social support had a significant relationship with self-care behavior (p= 0.03). Social support and self-care behavior show a positive correlation. In conclusion, involving family member in self-care management program of a patient with heart failure are needed.
Keywords: Heart Failure, Social support, Self-care behavior.
Name of Person Attending: Jwala Priyadarshini
Affiliation: Department of Biochemistry, Sri Venkateswara University, Tirupati, India
Paper Title: Food and Work Imbalance on Human Health
Abstract: The present study was an attempt to investigate the perceptions of research on the imbalance of food consumed and the amount of work done and its effects on health. The main objective of the study is to investigate the causes for the food and work imbalance and contribute the study for further scientific studies and research. It is reviewed and concluded that imbalance of food and daily work have adverse effects on health. The World Health Organisation (WHO) defines health as 'a state of complete physical, mental and social wellbeing and not merely the absence of disease or infirmity' (WHO, 1948) and 'Wellbeing' refers to a positive rather than neutral state, framing health as a positive aspiration. The health of the human population now a days is compromised majorly because the food consumed does not meet the amount of energy expelled through daily activities. This not only affects the normal physiological functions but also has adverse effects on mental health disturbing the immune system making the body susceptible to various diseases like diabetes, cardio vascular diseases, mental illness and various kinds of cancers affecting human population of different age groups. The main reason for the imbalance of food and work is urbanisation and use of electronics where there is less demand of mechanical energy in the first place following the high calorie food and sedentary lifestyle patterns that are changed with emerging trends in modern culture. The purpose of the study is to investigate, understand and create awareness that the balance of energy input and energy output will help build a healthy lifestyle.
Key words: Health, Nutrition, Exercise, Diseases, Energy imbalance.
Name of Person Attending: Professor Mome Spasovski
Affiliation: Institute of Social Medicine, University of Saints Cyril and Methodius, Medical Faculty, Skopje, North Macedonia
Paper Title: Health workforce mobility and Sustainable Development Goals in North Macedonia: the problem with the ‘brain drain’ of health workers
Abstract: Research Objectives: The migration of skilled and highly educated workforce from low and middle-income countries to high-income countries, also known as ‘brain drain’, is one of the most complex aspects of globalization. The ‘brain drain’ of health workforce poses significant challenges to the health industry and health coverage in source countries. The importance of the health workforce in the context of the SDGs (Goal 3) emphasizes the critical need to “substantially increase health financing and the recruitment, development, training, and retention of the health workforce”. This paper aims to critically review trends and factors relating to health workforce mobility in North Macedonia in order to better understand current possibilities and challenges and to contribute towards informing policy solutions and advancing the 2030 Agenda.
Name of Person Attending: Azam Bakhtiarian
Affiliation: Department of pharmacology,School of medicine, Tehran University of medical sciences, Tehran, Iran
Paper Title: Evaluation of isolated vascular response to 5HT1A, 5HT1B1D & 5HT2A receptors agonist & antagonist in chronic
Abstract: The main vascular abnormality seen in endotoxemia is impaired contractile responses to vasoactive agents. This study examines the aortic response to 5HT1A, 5HT1B1D & 5HT2A receptors agonist & antagonist in aortic rings of chronic endotoxemic rats. Chronic endotoxemia induced by intraperitoneal injection of 1 mg/kg lipopolysaccharide (Salmonella typhimurium) for 5 days. Control rats received intraperitoneal injection of saline (1 ml/kg) for 5 days. Rats divided into 3 groups. In first group, DOI hydrochloride used as an agonist & sarpogrelate hydrochloride as an antagonist of 5HT2A receptor. In second group, (R)-(+)-8-OH-DPAT hydrobromide used as an agonist & WAY100135 as an antagonist of 5HT1A receptor. In third group, Zolmitriptan used as an agonist & GR127935 hydrochloride hydrate as an antagonist of 5HT1B1D receptor. Thoracic aorta removed for pharmacological examination and placed in organ bath. Real time-PCR & histopathological study performed to investigate gene expression & tissue protein localization of receptors. Cumulative 8-OH-DPAT & zolmitriptan in separate experiments caused first-doses vasorelaxation in control group. The same treatments generated enhanced vasodilation during endotoxemia. The contractile response to DOI hydrochloride converted to relaxation response in endotoxin-treated group. PCR studies showed significantly enhanced expression of 5HT1A receptor gene in endotoxemic aorta while the expression of 5HT1B1D & 5HT2A receptor genes were diminished. Histopathological studies showed mild focal inflammation and damaged endothelium in endotoxemic aorta. In conclusion, data support the evidence for lipopolysaccharide-induced increase in endothelium-dependent relaxation & impaired vasoconstriction in aortic rings of endotoxemic rats.
Keywords: Endothelium, Vasodilation, Endotoxins, Aorta, Serotonin.
Name of Person Attending: Siti Yusrina Nadihah Jamaludin
Affiliation: School of Basic Medical Sciences, Faculty of Medicine, Universiti Sultan Zainal Abidin, Kuala Terengganu, Terengganu, Malaysia
Paper Title: The Role of Transient Receptor Potential Cation Channel subfamily V member 4 (TRPV4) in Colorectal Cancer
Abstract: The transient receptor potential cation channel subfamily V member 4 (TRPV4) is a non-selective calcium (Ca2+)-permeable channel which is expressed in many types of tissues. In addition to its roles in various physiological processes such as osmoregulation and mechanosensation, growing evidence suggests that TRPV4 is also involved in several aspects of tumourigenesis. Despite the reported roles of TRPV4 in several types of cancers, the role of TRPV4 in colorectal cancer has not been extensively assessed. This study aimed at exploring the potential role of TRPV4 in colorectal cancer cells. Quantitative real-time PCR analysis showed that TRPV4 mRNA levels were lower in HT-29 colorectal cancer cells than normal colon CCD-18Co cells. In contrast, TRPV4 mRNA was undetected in HCT-116 colorectal cancer cells. Pharmacological activation of TRPV4 using GSK1016790A promoted the proliferation of HT-29 cells while TRPV4 inhibition using RN 1734 decreased their proliferation, as assessed by the MTT cell proliferation assay. Co-treatment with RN 1734 attenuated GSK1016790A-induced increases in proliferation in HT-29 cells. Cell cycle analysis by flow cytometry revealed that pharmacological modulation of TRPV4 had no pronounced effect on the cell cycle progression in HT-29 cells. Analysis from the Annexin-V/PI double-staining assay demonstrated that both activation and inhibition of TRPV4 channel could promote the death of HT-29 cells, despite at different degrees of cell death induction. Altogether, these findings suggest divergent TRPV4 mRNA expression levels between human colorectal cancer cells and normal colon cells. Pharmacological modulation of TRPV4 appears to alter the proliferation of HT-29 cells and induces cell death in this cell line. TRPV4 may represent a promising drug target for the treatment of colorectal cancer.
Keywords: TRPV4; colorectal cancer; proliferation; cell cycle; cell death.
Name of Person Attending: Priscilla Suresh
Affiliation: Department of Zoology, Bishop Heber College, Tiruchirappalli, India
Paper Title: Evaluation of Antiurolithiatic Potential of Methanolic Fruit Extract of Terminalia Chebula Retz. on the Kidney Stone Struvite Crystals
Abstract: Kidney stone disease is a common urinary stone disorder in humans. Urolithiasis is the formation of stones in the urinary tract that prominently cause variable degree of pain, bleeding, and further may lead to secondary infection. Kidney stones form upon the supersaturation of the urine with calcium and other salts especially oxalate. The size of the stone can increase and obstruct in the urinary system. Although the most effective treatment of kidney stone is extracorporeal shock wave lithotripsy, the side effects of this method are grave and can lead to recurrence of kidney stones. Therefore alternative treatments are of high interest means by using medicinal plants.
Terminalia chebula is a medium to large deciduous tree. The fruits are smooth ellipsoid to ovoid drupes, yellow to orange-brown in colour, with a single angled stone. The fruits of T. chebula were collected from Pachamalai, Tamilnadu, India. The growth characteristics of the most common types of urinary stones struvite crystals and the effect of methanol extracts of fruit of T. chebula has been studied.
Phytochemical compounds such as terpenoids, flavonoids, saponins, tannins, glycosides, coumarins, leucoanthocyanin, xanthoprotein are present in methanol extracts of fruits of
T.chebula. With an increase in the concentration of the fruits of T. chebula from 1% to 5% (v/v), the weight of the formed struvite crystals were gradually reduced from 1.205gm to 0.25gm due to the inhibitory effect of the fruits of T. chebula under in vitro conditions. T.chebula fruits extract contained 2.1 g of alkaloids, 0.3 g of flavonoids, 1.24 g of terpenoids. Crystallization characteristics of struvite crystals in the fruits of T. chebula have reported using FTIR techniques. In Control the band at 1679 cm-1 is due to C=O group. The peak at 1436 cm-1 is due to Methyl C-H Asymmetric and Symmetric bend and the peak at 891 cm-1 is due to Silicate ion
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