Eurasia Research Quarterly Newsletter: STRA (October 2019- December 2019)
Updated: Jan 16, 2020
Dear STRA Members,
Greetings and sincere thanks for your patronage and support. STRA has now grown to 11762 followers and members from 55 countries
We are glad to present you our latest edition of the newsletter. The newsletter showcases the associations of current and upcoming endeavors.
STRA has successfully organized following International conferences in the period of October 2019- December 2019:
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Eurasia Research International Conference began with opening remarks by Honourable Keynote speaker highlighting the main context on Teaching Issues.
The main aim of this conference was:
Advancement of academic knowledge through encouraging research activities.
To create a global community of scholars
Promotion of innovative thinking and ideas on a global platform
Making knowledge accessible to one and all using technology and ideas
Contributing to making the world a better place to live
Our worthy Keynote speakers open up the conference enlightening participants with their speech. Here is our list of keynote speakers who participated in our conference.
Eurasia Research makes continuous efforts in transforming the lives of people around the world through education, application of research & innovative ideas. In order to Promote Young Researchers, Eurasia Research International conferences, Provides Young Research Scholarship in the form of a full Registration fee waiver to participate in such events. This gives immense encouragement to the researchers who have brilliant ideas to exhibit their research work on the International platform. Eurasia Research aims for promoting research and talent of scholars by giving the scholarship to 5 selected applicants for each conference.
Name of Person Attending: Priya Patel Affiliation: Department of Pharmaceutical Sciences, Saurashtra University, Rajkot, Gujarat, India
Paper Title: Formulation and characterization of Silibinin loaded Inhalation Nanoparticle drug delivery system for the treatment of Lung cancer
Abstract: The purpose of the present study was to optimize Silibinin loaded chitosan (CS) nanoparticles using a modified ionic gelation method by application of quality by design (QbD) approach. Based on the risk assessment, the effect of three variables, that is CS %, tripolyphosphate % and rate of addition of Chitosan were studied on critical quality attributes (CQAs); particle size, entrapment efficiency, CDR at 1 Hr., T50 and T90. Box Behnken design was implemented for the design of experimentation with 15 runs. Prepared nanoparticles were characterized for particle size, Zeta potential, polydispersity index, entrapment efficiency, in-vitro release study, FTIR, differential scanning calorimetric, X-ray diffraction along with scanning electron microscopy (SEM). X-ray diffraction analysis revealed a transformed physical state of silibinin after encapsulation. Based on the QbD approach, design space (DS) was optimized with a range of selected variables with entrapment efficiency > 50% w/w and a particle size between 300 to 400 nm, CDR at 1 hr. between 10% to 15%, T50 between 5 – 6 hrs. and T90 between 11 – 12 hrs. In-vitro drug release followed dual mechanism via, diffusion and polymer erosion shows 95.63% in 8 hrs. By SEM Study its shows particles are spherical in shape and Size distribution agreement for prepared metered dose inhaler was better (MMAD =3.3 ± 0.17 µm with Fine particle fraction from 48% to 62% investigated by cascade impactor indicate deep targeting of FP to alveoli. The concentration of Silibinin in the lung reached a maximum level at 0.5 h post Formulation Inhalation. A 17.8-fold larger area under the curve of Nanoparticle was achieved compared to that of the solution of silibinin. Tumor cells in the lungs were observed in approximately 98 % rats after 5 months of NNK treatment, as evident by histopathological analysis. This rodent model showed slow progression of lung tumors which has helped us to assess early indicators of oxidative damage in the lungs by studying the levels of lipid peroxidation and antioxidant parameters. LPO was elevated by 46.94 %, SOD, CAT, GSH and GR activity was decreased by 48.67 %, 22.04 %, 21.46 %, and 20.85 %, respectively in the serum of NNK treated rats when compared with control. These findings suggest that increased oxidative stress can represent a risk factor for the development of lung cancer. Silibinin loaded formulations showed inhibitory effects against A549 cells in a dose- and time-dependent manner for 24, 48, and 72 h. IC50 of Silibinin loaded liposomal nanoparticles on the A549 lung cancer cell line showed that systems could be useful in the treatment of lung cancer. There were no significant changes that occurred in the physical properties of nanoparticles during 6 month storage period. Containers also fulfilled all the requirements. Inhalation nanoparticles were prepared successfully using the QbD approach with the understanding of the high-risk process and formulation parameters involved and optimized DS with a multifactorial combination of critical parameters to obtain predetermined nanoparticle specifications. These results indicate that nanoparticle may be promising lung- targeting drug carriers for lipophilic drugs such as Silibinin.
Key Words: Modified Ionic gelation, Box Behnken design; QbD approach, Particle size, In- vitro drug release
Name of Person Attending: Abu Naser Mohammad Saif
Affiliation: Department of Management Information Systems, University of Dhaka, Dhaka, Bangladesh
Paper Title: Impact of Green Supply Chain Management on Business Performance and Environmental Sustainability: Case of an Emerging Country
This study discovers the impact of green supply chain management (GSCM) practices on business performance and environmental sustainability. Cost and profit are the two important indicators of business performance. On the other hand, environmental sustainability is expressed by waste disposal, resource consumption, and greenhouse gas emission. Primary data was collected through the distribution of links and direct interaction with participants. A structured questionnaire was used for data collection. This study found that the impact of the implementation of GSCM practices differs on cost, profit, waste disposal, resource consumption, and greenhouse gas emission. GSCM practices have a significant impact on greenhouse gas emissions. GSCM practices also have a statistically significant impact on cost, waste disposal, and resource consumption. The impact of GSCM practices on profit was statistically insignificant. It was found that lack of IT implementation, high cost of waste disposal, uncertainty and competition in the market, resistance to change and lack of top management support are the major barriers to implement GSCM practices in Bangladesh.
Keywords: GSCM, cost, profit, business performance, environmental sustainability.
In each, Eurasia International Conference, Best Paper Award is given to Best Researches. In the Teaching and Education Research Association (TERA), the Best paper award is given to the participants with the best scholarly paper submitted and presented at the conference.
Name of Person Attending: Yousuf Alkhezi Affiliation: Department of Mathematics, The Public Authority for Applied Education and Training (PAAET), Kuwait
Paper Title: The Geometric Algebra and Homotopy
Abstract: This paper is an investigation into the properties and applications of Geometric algebra and to examine new property called the pinched homotopy. That there is much new to say on the subject. It is the computational power brought to the manipulation of these objects that makes geometric algebra interesting and worthy of study.
Keywords: Geometric Algebra, Complex, Pinched, Null homotopy.
Name of Person Attending: Sankalp Arpit Affiliation: School of Energy Science and Engineering, IIT Kharagpur, Kharagpur, India
Paper Title: Assessment of Sustainability Indicators of Two Gas Turbine Plants with Naphtha and Naphtha-Rfg Mixture as
Abstract: The aim of the present paper is to determine the sustainability aspects of a gas turbine engine (GT) based power plant. For this purpose, exergetic sustainability indicators are calculated for two GT power plant configurations, case A for Naphtha based power plant, case B for Naphtha-Residual fuel gas (Rfg) mixture based power plant. The investigated sustainability indicators are exergy efficiency, waste exergy ratio, environmental effect factor, and exergetic sustainability. Results show that exergetic sustainability index is obtained as 0.36 for case A and 0.24 for case B. The reason being case B has high exergy destruction as compared to case A.
Keywords: Exergy, naphtha, residual fuel gas, sustainability analysis
Name of Person Attending: Manoj Kumar Ghosal
Affiliation: Professor, Department of Farm Machinery and Power, Orissa University of Agriculture and Technology, Bhubaneswar, Odisha, India
Paper Title: Performance of Solar Photovoltaic Module through Combined Air and Water Cooling in Warm and Humid climatic Condition of India
Abstract: A study was conducted to evaluate the performance of a solar photovoltaic module through combined air and water cooling arrangements in warm and humid climatic condition i.e. in Odisha in India during winter and summer months. Solar photovoltaic system requires neither fuel nor produces any pollutant resulting in its increased importance in today’s energy sector. Generation of electricity from solar photovoltaic (PV) system is a function of the efficiency of the photovoltaic (PV) module and other factors influencing its efficiency. Temperature among the various factors affecting the efficiency of the PV module is the major parameter causing the effects on the efficiency of the PV module and power output. With the exposure of PV module to sunlight, the amount of energy from the sun converted to useful energy is about 31 %, a greater percentage is changed to heat energy, which tends to make the temperature of the module to rise and thus leads to a reduction in the generation of electricity by the module. This energy causes an increase in the temperature of the module and is wasted as heat which ultimately damages the material used to fabricate the PV module and hence reduces the life span of the cell as well as its conversion efficiency. To enhance the efficiency and power output from the module, the cooling arrangements such as air cooling, water cooling, and combined air and water cooling were incorporated and their effectiveness was compared without any cooling device. From the experiments, it was found that the efficiencies of the solar modules were increased in the range of 8-11 %, 12-15% and 16-20% in air, water and combined air and water cooling respectively compared to without cooling on a clear day.
Keywords: Solar Photovoltaic module, Cooling of the photovoltaic module, Efficiency of the photovoltaic module, Tilt angle for photovoltaic module
Name of Person Attending: Mohd Azizul Ladin
Affiliation: Faculty of Engineering, Universiti Malaysia Sabah, Sabah, Malaysia
Paper Title: Pilot Study for The Modelling Of Congestion Pricing in Kota Kinabalu, Sabah
Abstract: Congestion pricing is a policy at which road users being charged with a certain amount for using a particular road during peak hours. It is as much about meeting the demand of car drivers for road space as allocating road space between road users. It has been successfully implemented in some other countries such as Stockholm, London, and Singapore with the various schemes of congestion pricing. Hence, the main aim of this pilot study is to evaluate and create a model based on the willingness of the Kota Kinabalu City residents’ to shift to public transport due to the implementation of congestion pricing. A total of 60 respondents were randomly chosen within Kota Kinabalu City. Data collection is being conducted using a stated preference survey and analyzed with Microsoft Office Excel 2010 in order to conduct a regression analysis and develop a logistic transport model analysis. It is found that the number of people who willing to shift to public transport is parallel with the congestion charge amount. The results from this pilot study indicate that 71.67% of respondents are willing to shift to public transport when the congestion charge price is RM4.00. This study can give a contribution to further transportations planning in order to achieve sustainable transportations in Kota Kinabalu, Sabah.
Keywords: Pilot study, congestion charge, public transport, modal shift, logistic model
Name of Person Attending: Georgia Garani
Affiliation: Department of Digital Systems, University of Thessaly, Larissa, Greece
Paper Title: The Development of a Clinical Data Warehouse for Lung and Ovarian Cancer Data
Abstract: Despite the collection of huge amounts of data by the healthcare industry, effective decision making is not achieved for serving medicine science. Data warehousing technology can be applied for collecting and managing clinical data from varied sources to provide meaningful insights for physicians and administrators. When considering the size and complexity of cancer data, a clinical data warehouse system can shed light on prevention, diagnosis and treatment processes by using On-line Analytical Processing (OLAP) tools for interactive analysis of multi-dimensional data at various granularity levels. In this study, a clinical data warehouse is developed for lung cancer data which were received kindly from the American National Cancer Institute (NCI). The lung and ovarian cancer data have brought into certain formats, cleaned from errors and repetitions. The clinical data warehouse is designed to respond efficiently to all types of queries by adopting the fact constellation schema model. A number of different OLAP queries are expressed using the proposed approach.
Keywords: Clinical data warehouse, OLAP, lung cancer data, ovarian cancer data, fact constellation schema.
Name of Person Attending: Salman Azhar
Affiliation: Lahore University of Management Sciences (LUMS), Lahore, Pakistan
Paper Title: Evaluation of Homa: A Receiver Driven Transport Protocol for Data Centers
Abstract: This paper deals with the means of transferring energy from the input to the output. The buck-boost converter is considered as a maximum power point tracker or power equilibrium device used between the photovoltaic solar system and the battery by supplying the desired power for the stand-alone system requirements. The whole system energy is assigned by SLP190S-24 High-Efficiency Monocrystalline PV module based Perturb and Observe (P&O) MPPT algorithm with a selected lead-acid battery bank of 24 Volts. In order to achieve this energy transfer with minor energy losses, the Buck-Boost converter with the switching frequency of 25Khz is designed for charging the lead battery applied in a standalone system. The MATLAB SIMULINK is used to validate the accuracy and effective the ess of the designed Buck-Boost converter simulation results. The result clings to the value of 99.72% for the combined Tracking and conversion efficiencies.
Keywords: Photovoltaic solar panel, Buck-Boost Converter, Perturb and Observe (P&O) algorithm, Battery.
Name of Person Attending: Haji Muhammad Shoaib Khan
Affiliation: Pharmacy Department, The Islami University of Bahawalpur, Bahawalpur, Pakistan
Paper Title: Characterization of Curcuma zedoaria root extract for bioactive phytochemicals and its assessment for multiple skincare potentials: a non-invasive approach using advanced imaging and bioengineering methods
Abstract: Numerous plants, because of being a rich source of antioxidants including flavonoids and polyphenols, have been used in folk medicine but they have infrequently been used topically to combat skin-damaging conditions. Currently, there is no study reporting the cosmeceutical beneficial effects of gellified emulsion system of Curcuma zedoaria (CZ) root extract in healthy humans. The current study was an active endeavor to characterize Curcuma zedoaria root extract and to probe the skincare effects of its emulgel for reviving and improving facial skin properties. METHODS: Initially Curcuma zedoaria root extract was evaluated for secondary metabolites, phenolic and flavonoids contents; antioxidant and tyrosinase inhibition activities. After developing CZ extract emulgel system, its in-vitro sunscreen factor was determined. In-vivo performance of test emulgel was evaluated for 12 weeks in thirteen healthy humans using a single-blinded, placebo-controlled and split-faced trial. Non-invasive bioengineering and advanced imaging techniques were used for clinical evaluation. RESULTS: The experiment showed that Curcuma zedaria (CZ) root extract has valuable secondary metabolites; noteworthy amount of phenolic and flavonoid compounds; and eminent antioxidant and anti-tyrosinase potential. The prepared CZ emulgel manifested significant improvement (p˂0.05) associated with skin parameters including erythema, melanin, hydration, sebum and facial pores. CONCLUSIONS: Curcuma zedoaria root extract emulgel, being an imperative strategy for improvisation of skin-damaging conditions, proved to have therapeutic potential in the cosmetic field.
Keywords: Curcuma zedoaria; Single-blind method; Non-invasive bioengineering techniques; Skin care.
Name of Person Attending: Muhammad Younis
Affiliation: Institute of Life Sciences, Southeast University, Nanjing, China
Paper Title: Iguratimod Encapsulated PLGA-NPs Improves Therapeutic Outcome in Glioma, Glioma Stem-Like Cells and
Temozolomide Resistant Glioma Cells
Abstract: Glioma is the most common neoplasm of the central nervous system, with the highest mortality rate. The present study was designed to examine the therapeutic effect of Iguratimod (IGU) encapsulated- poly (lactic-co-glycolic acid) PLGA nanoparticles (IGU-PLGA-NPs), which showed inhibition of glioma cells proliferation both in vitro and in vivo. IGU was encapsulated in PLGA nanoparticles with an average size of 100-200nm were prepared using a modified double-emulsion (W1/O/W2) method. Cell Counting Kit-8 (CCK-8) analysis of Glioma cancer cells and glioma stem-like cells (GSCs), demonstrated significant inhibition of their growth treated with IGU-PLGA-NPs. IGU-PLGA-NPs inhibit migration in glioma cells as well as tumorsphere formation in GSCs. Treatment with IGU-PLGA-NPs showed a significant decrease in tumor growth through the apoptotic pathway in mice model without any visible organ toxicity and it can successfully cross the blood-brain barrier (BBB). Most Importantly, IGU-PLGA-NPs significantly depleted the growth of U251 Temozolomide-resistant (U251TMZ-R) cells.
Keywords: Glioma, PLGA, IGU, Therapy
Name of Person Attending: Inchan Park
Affiliation: Department of Convergence Design Lab., Media4thone Ltd., Seoul, Korea
Paper Title: Omni-channel Fashion Shopping Service Business Model for Promotion of Small Fashion Retail
Abstract: This study attempted to seek out a business model that could restore small fashion businesses that have been forced out to the outskirts because of gentrification. In the Republic of Korea, there used to be many fashion streets along which small retail fashion stores were clustered. Right now, however, it is hard to find traces of such small retail fashion stores. This study has searched for diverse ideas on the services which can help people find a small retail fashion store, and the results found three plans: i) To launch a channel to attract people who are interested in fashion, ii) to develop a mobile device-based service which is familiar to young users, iii) to utilize media which appeal to young people. Consequently, this study selected virtual fitting as such an interesting medium and proposed an omnichannel fashion shopping service business model that connects both offline (virtual fitting booth) and mobile (fitting experience & purchase support app) channels. This service provides the latest fashion shopping information and high-quality fashion curating service. In addition, it would offer a new communication channel with customers to small retail fashion stores and boost small fashion business.
Keywords: Omni-Channel, Immersive VR, Virtual Fitting, Fashion Curating, Service Design
Name of Person Attending: Laith Al Any
Affiliation: Department of Engineering and Computing, National University, San Diego, U.S.A.
Paper Title: Guidelines for Software Design Practices
Abstract: Design is one of the most creative tasks in developing software systems. Designers are responsible for making all major decisions. Many modeling aspects including analytical, structural, behavioral, intuitive, algorithmic, artistic, technical, graphical, cognitive, mathematical, psychological and programming models need to be considered in the development process of an effective design especially for complex systems because software complexity needs to be addressed through design. Software designers are required to be involved directly or indirectly in all major software development activities. This paper critically reviews past practices in software design and presents a set of guidelines for achieving creative solutions to software design problems. It also suggests how to design representations can be improved by extending current practices.
Keywords: Behavioral models, cognitive load, complexity, iterative process, user experience.
Name of Person Attending: Handoko Kuncoro
Affiliation: Balai Besar Keramik, Badan Penelitian dan Pengembangan Industri, Bandung, Indonesia
Paper Title: Study on Structure, Stability and Ionic Conductivity of LZTP.4LO Solid Electrolyte
Abstract: This study aims to evaluate the structure, stability and ionic conductivity of the solid electrolytes of the Nasion LMTP families with M = Z (Zr). In the synthesized electrolyte we also added Lithium oxide inside the LZTP to improve its conductivity. The evaluations have been performed by comparing the characteristics of LZTPs to ordinary material of Nasicon solid electrolyte (i.e. LATP type). The synthesis of LZTP.4LO has been carried out using the powder metallurgy method through the stages of making TiP, making LTP, making LZTP and adding Lithium oxide. The XRD pictogram analyses have indicated that the LZTP crystal structure that was synthesized had a structure in accordance with the type of LATP in previous studies and the ICSD95979 standard for LTP. The results of SEM micrograph analyses have shown that the microstructure for both LATP.4LO and LZTP.4LO was cuboid with a side length between 0.25-2 microns. The results of the stability analysis of the Cole-cole plot have indicated that the stability of LZTP.4LO ion conduction was better compared to other types of LATP. Measurements of ionic conductivity from a range of 1000 Hz to 4000 Hz at room temperature have shown that ion conduction of LZTP.4LO solid electrolytes was more stable than LATP.4LO and was almost constant around 7-8 x 10-4 S/cm.
Name of Person Attending: Deepak Panghal
Affiliation: Department of Fashion Technology, National Institute of Fashion Technology, India
Paper Title: A framework for implementation of Predictive Maintenance (PdM) System for Apparel Manufacturing Industry
Abstract: The garment manufacturing industry is a highly machinery dependent industry. Machine maintenance is a very important task in the garment manufacturing industry. In the current production setups, even a machine downtime might lead to serious production problems. Effectively designed efforts to update maintenance management have become a necessity. Therefore, the purpose of this paper is:
• To identify the various steps involved in the implementation of PdM
• To develop a framework for implementation of PdM for apparel manufacturing Industry
The various steps like Machine Criticality Analysis Criteria, Architecture Development, Hardware and software identification, and system deployment are disused in length.
A PdM system is proposed to automate the process of anomaly detection for critical machines, hence improving the machine management and decreasing unscheduled downtime of the machines. The proposed system can effectively optimize the traditional maintenance programs by a selection of the critical machine, identification of failures in the machine, and prediction of failure before the breakdown.
Keywords - Predictive Maintenance, Machine Learning
Matter: International Journal of Science & Technology
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